二苯基氯化碘盐
交易须知
diphenyleneiodonium chloride产品活性：diphenyleneiodonium chloride 是一种 nadph 氧化酶 (nox) 抑制剂，也是一种 trpa1 激活剂，ec50 值在 1 至 3 μm 之间。
研究领域：membrane transporter/ion channel | metabolic enzyme/protease
作用靶点：trp channel | nadph oxidase
in vitro: diphenyleneiodonium chloride is a nadph oxidase (nox) inhibitor and also functions as a trpa1 activator with an ec50 of 1 to 3 μm. application of diphenyleneiodonium chloride to hek-trpa1 cells at a concentration ranges of 0.03 to 10 μm effectively induces a ca2+ response. however, diphenyleneiodonium chloride fails to evoke a ca2+ response in control hek cells, even at a relatively high dose of 10 μm. when diphenyleneiodonium chloride is included in the co-cultures, lipopolysaccharide (lps)-induced preol apoptosis is significantly inhibited. treatment with diphenyleneiodonium chloride is found to significantly attenuate the lps-induced o2- production by 2.0-fold, reducing it to within 27% of the controls.
in vivo: intraplantar injection of 2 mm diphenyleneiodonium chloride to the hindpaw causes licking or biting behavior. diphenyleneiodonium chloride treatment immediately or 24 h after lipopolysaccharide (lps) injection significantly attenuates the lps-induced loss of o4 positive cells. treatment with diphenyleneiodonium chloride either immediately or 24 h after lps injection significantly ameliorates the lps-induced disorganization of the white matter nerve fibers. however, treatment with dpi 48 h after lps injection does not appear to correct the lps-induced white matter damage. dpi treatment either immediately or 24 h after lps injection significantly reduces the accumulation of both gp91phox and p67phox in the membrane fraction.
相关产品：anti-aging compound library | metabolism/protease compound library | bioactive compound library plus | membrane transporter/ion channel compound library | rosiglitazone | capsaicin | setanaxib | capsazepine | eipa | probenecid | skf-96365 hydrochloride | hc-030031 | hc-067047 | gsk1016790a | amg9810 | pf-4840154 | rn-1734 | sar7334 | vas2870 | amg 517 | gsk2193874 | icilin | rq-00203078 | sb-366791 | hc-070 | asivatrep | ml204 | pico145 | cardamonin | am-0902 | glx351322 | jnj-17203212 | a-967079
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diphenyleneiodonium chloride产品活性：diphenyleneiodonium chloride 是一种 nadph 氧化酶 (nox) 抑制剂，也是一种 trpa1 激活剂，ec50 值在 1 至 3 μm 之间。
研究领域：membrane transporter/ion channel | metabolic enzyme/protease
作用靶点：trp channel | nadph oxidase
in vitro: diphenyleneiodonium chloride is a nadph oxidase (nox) inhibitor and also functions as a trpa1 activator with an ec50 of 1 to 3 μm. application of diphenyleneiodonium chloride to hek-trpa1 cells at a concentration ranges of 0.03 to 10 μm effectively induces a ca2+ response. however, diphenyleneiodonium chloride fails to evoke a ca2+ response in control hek cells, even at a relatively high dose of 10 μm. when diphenyleneiodonium chloride is included in the co-cultures, lipopolysaccharide (lps)-induced preol apoptosis is significantly inhibited. treatment with diphenyleneiodonium chloride is found to significantly attenuate the lps-induced o2- production by 2.0-fold, reducing it to within 27% of the controls.
in vivo: intraplantar injection of 2 mm diphenyleneiodonium chloride to the hindpaw causes licking or biting behavior. diphenyleneiodonium chloride treatment immediately or 24 h after lipopolysaccharide (lps) injection significantly attenuates the lps-induced loss of o4 positive cells. treatment with diphenyleneiodonium chloride either immediately or 24 h after lps injection significantly ameliorates the lps-induced disorganization of the white matter nerve fibers. however, treatment with dpi 48 h after lps injection does not appear to correct the lps-induced white matter damage. dpi treatment either immediately or 24 h after lps injection significantly reduces the accumulation of both gp91phox and p67phox in the membrane fraction.
相关产品：anti-aging compound library | metabolism/protease compound library | bioactive compound library plus | membrane transporter/ion channel compound library | rosiglitazone | capsaicin | setanaxib | capsazepine | eipa | probenecid | skf-96365 hydrochloride | hc-030031 | hc-067047 | gsk1016790a | amg9810 | pf-4840154 | rn-1734 | sar7334 | vas2870 | amg 517 | gsk2193874 | icilin | rq-00203078 | sb-366791 | hc-070 | asivatrep | ml204 | pico145 | cardamonin | am-0902 | glx351322 | jnj-17203212 | a-967079
MedChemExpress LLC
郑先生
86-021-58955995
17321200539
江苏大功率温控器批发零售服务好的公司在这里等你到来
客车)(路桥到岳池县大巴长途汽车^票价合理
“跑马圈地”式开拓中国市场 品牌们增长依托中国？
优质直销 供应物美价廉 LED地埋灯
婴儿用品tpe料
二苯基氯化碘盐
少儿艺术培训加盟，东方童画美术教育人气火爆的知名品牌
四川乐山市哪里有圆柱模出租
嵩晟养生杯 养生杯 易吸收 排毒养颜
呼吸麻醉机 医用呼吸麻醉设备
沂蒙红梨基地浅谈五角枫虽有短板，仍是用于绿化的好树种
河南小区直饮水生产厂商 浩盛水设备品质有把握
天翼智慧小区（简称智慧小区）
黑龙江省安全可靠伸缩梯，招商加盟物美价廉售后方便
从南昌到朔州物流有限公司欢迎您√
洛龙区口碑好的小吃培训班价格低-七里香培训
现代城市建设杜绝使用放炮施工肿么办!岩石分裂机的结构
可定制t型钢 t型钢25*25*3 H型钢剖分现货
标致408 2011款 1.6L 手动 舒适型
河北防腐木托 河北腾尚木托厂